MAEA Antibody

Catalog Number:

33945

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q7L5Y9
NCBI Gene ID: 10296

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human MAEA.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total MAEA protein.

Applications:

WB

Background:

Plays a role in erythroblast enucleation and in the development of the mature macrophages. Mediates the attachment of erythroid cell to mature macrophages, in correlation with the presence of MAEA at cell surface of mature macrophages; This MAEA-mediated contact inhibits erythroid cells apoptosis. Participates to erythroblastic island formation, which is the functional unit of definitive erythropoiesis. Associates with F-actin to regulate actin distribution in erythroblasts and macrophages. May contribute to nuclear architecture and cells division events.

Ota T., Nat. Genet. 36:40-45(2004).
Hanspal M., Blood 92:2940-2950(1998).
Bala S., Biochem. Biophys. Res. Commun. 342:1040-1048(2006).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF