STEA3 Antibody

Catalog Number:

33932

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q658P3
NCBI Gene ID: 55240

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human STEA3.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total STEA3 protein.

Applications:

WB IF

Background:

Endosomal ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Participates in erythroid iron homeostasis by reducing Fe3+ to Fe2+. Can also reduce of Cu2+ to Cu1+, suggesting that it participates in copper homeostasis. Uses NADP+ as acceptor. May play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. Indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCTP.

Passer B.J., Proc. Natl. Acad. Sci. U.S.A. 100:2284-2289(2003).
Korkmaz C.G., Oncogene 24:4934-4945(2005).
Steiner M.S., Cancer Res. 60:4419-4425(2000).

References:

appl_detail:

Western blotting: 1:500~1:3000

Immunofluorescence: 1:100~1:500

Datasheet PDF