DOK7 Antibody

Catalog Number:

33918

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q18PE1
NCBI Gene ID: 285489

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from N-terminal of human DOK7.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total DOK7 protein.

Applications:

WB IHC IF

Background:

Probable muscle-intrinsic activator of MUSK that plays an essential role in neuromuscular synaptogenesis. Acts in aneural activation of MUSK and subsequent acetylcholine receptor (AchR) clustering in myotubes. Induces autophosphorylation of MUSK.

Okada K., Science 312:1802-1805(2006).
Ota T., Nat. Genet. 36:40-45(2004).
Beeson D., Science 313:1975-1978(2006).

References:

appl_detail:

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100
Immunofluorescence: 1:100~1:500

Datasheet PDF