p97 MAPK Antibody

Catalog Number:

33914

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q16659
NCBI Gene ID: 5597

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human p97 MAPK.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total p97 MAPK protein.

Applications:

WB IF

Background:

Atypical MAPK protein. Phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK3/MAPK6 is phosphorylated at Ser-189 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK3/MAPK6. May promote entry in the cell cycle By similarity.

Zhu A.X., Mol. Cell. Biol. 14:8202-8211(1994).
Meloche S., Oncogene 13:1575-1579(1996).
The MGC Project Team, Genome Res. 14:2121-2127(2004)

References:

appl_detail:

Western blotting: 1:500~1:3000

Immunofluorescence: 1:100~1:500

Datasheet PDF