TAF1A Antibody

Catalog Number:	33901
other_names:	TATA box-binding protein-associated factor 1A; TBP-associated factor 1A; TBP-associated factor RNA polymerase I 48 kDa; TAFI48; Transcription factor SL1
Amount:	100μg
calculated_mw:
host_species:	Rabbit
Price:	$319
Swiss-Prot No:	Swiss-Prot: Q15573 NCBI Gene ID: 9015
Form of Antibody:	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/Stability:
Immunogen:	Synthesized peptide derived from internal of human TAF1A.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity/Sensitivity:	The antibody detects endogenous levels of total TAF1A protein.
Applications:	WB
Background:	Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits. Comai L., Science 266:1966-1972(1994). Ota T., Nat. Genet. 36:40-45(2004). Gregory S.G., Nature 441:315-321(2006).
References:
appl_detail:	Western blotting: 1:500~1:3000
	Datasheet PDF

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