Glucokinase Regulator Antibody

Catalog Number:

33879

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q14397
NCBI Gene ID: 2646

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human Glucokinase Regulator.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total Glucokinase Regulator protein.

Applications:

WB

Background:

Inhibits glucokinase (GCK) by forming an inactive complex with this enzyme. The affinity of GCKR for GCK is modulated by fructose metabolites: GCKR with bound fructose 6-phosphate has increased affinity for GCK, while GCKR with bound fructose 1-phosphate has strongly decreased affinity for GCK and does not inhibit GCK activity.

Warner J.P., Mamm. Genome 6:532-536(1995).
Hayward B.E., Genomics 49:137-142(1998).
Rieder M.J., Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases.

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF