CBF β Antibody

Catalog Number:

33875

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q13951
NCBI Gene ID: 865

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human CBF β.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total CBF β protein.

Applications:

WB IHC

Background:

CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, LCK, IL3 and GM-CSF promoters. CBFB enhances DNA binding by RUNX1.

Hajra A., Genomics 26:571-579(1995).
Liu P., Science 261:1041-1044(1993).
Warren A.J., EMBO J. 19:3004-3015(2000).

References:

appl_detail:

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100

Datasheet PDF