TLE2 Antibody

Catalog Number:

33855

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q04725
NCBI Gene ID: 7089

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human TLE2.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total TLE2 protein.

Applications:

WB

Background:

Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES By similarity.

Stifani S., Nat. Genet. 2:119-127(1992).
Grimwood J., Nature 428:529-535(2004).
Grbavec D., Eur. J. Biochem. 258:339-349(1998).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF