ST5 Antibody

Catalog Number:

33837

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P78524
NCBI Gene ID: 6764

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human ST5.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total ST5 protein.

Applications:

WB

Background:

Guanine nucleotide exchange factor (GEF) which may activate RAB9A and RAB9B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. May be involved in cytoskeletal organization and tumorogenicity. Isoform 1 seems to be involved in a signaling transduction pathway leading to activation of MAPK1/ERK2. Isoform 3 may block ERK2 activation stimulated by ABL1. Isoform 3 may alter cell morphology and cell growth.

Lichy J.H., Nucleic Acids Res. 24:4700-4708(1996).
Amid C., Cytogenet. Cell Genet. 93:284-290(2001).
Lichy J.H., Cell Growth Differ. 3:541-548(1992).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF