MAFF Antibody

Catalog Number:

34118

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q9ULX9
NCBI Gene ID: 23764

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human MAFF.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total MAFF protein.

Applications:

IHC

Background:

Interacts with the upstream promoter region of the oxytocin receptor gene. May be a transcriptional enhancer in the up-regulation of the oxytocin receptor gene at parturition. Since it lacks a putative transactivation domain, it may behave as a transcriptional repressor when it dimerize among himself. May also serve as a transcriptional activator by dimerizing with other (usually larger) basic-zipper proteins and recruiting them to specific DNA-binding sites. May be involved in the cellular stress response.

Ota T., Nat. Genet. 36:40-45(2004).
Moran J.A., Biochem. J. 361:371-377(2002).
Dunham I., Nature 402:489-495(1999).

References:

appl_detail:

Immunohistochemistry: 1:50~1:100

Datasheet PDF