AP2C Antibody

Catalog Number:

34004

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q92754
NCBI Gene ID: 7022

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human AP2C.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total AP2C protein.

Applications:

WB

Background:

Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC.

Williamson J.A., Genomics 35:262-264(1996).
McPherson L.A., Proc. Natl. Acad. Sci. U.S.A. 94:4342-4347(1997).
Deloukas P., Nature 414:865-871(2001).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF