ATBP3 Antibody

Catalog Number:

33949

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q7Z7A3
NCBI Gene ID: 90353

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from C-terminal of human ATBP3.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total ATBP3 protein.

Applications:

WB

Background:

Plays a central role in 2-thiolation of mcm5S2U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.

Yousef G.M., Submitted (APR-2003) to the EMBL/GenBank/DDBJ databases.
The MGC Project Team, Genome Res. 14:2121-2127(2004).
Beausoleil S.A., Nat. Biotechnol. 24:1285-1292(2006).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF