CEBPB Antibody

Catalog Number:

33697

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P17676
NCBI Gene ID: 1051

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human CEBPB.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total CEBPB protein.

Applications:

WB

Background:

Important transcription factor regulating the expression of genes involved in immune and inflammatory responses. Binds to regulatory regions of several acute-phase and cytokines genes and probably plays a role in the regulation of acute-phase reaction, inflammation and hemopoiesis. The consensus recognition site is 5'-T[TG]NNGNAA[TG]-3'. Plays an important role in adipose tissue differentiation. Regulates the transcriptional induction of peroxisome proliferator-activated receptor gamma (PPARG) as well as other adipogenesis key player genes. Isoform 3:acts as a dominant negative through heterodimerization with isoform 2.

Akira S., EMBO J. 9:1897-1906(1990).
Wan D., Proc. Natl. Acad. Sci. U.S.A. 101:15724-15729(2004).
Deloukas P., Nature 414:865-871(2001).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF