hnRNP L Antibody

Catalog Number:

33682

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P14866
NCBI Gene ID: 3191

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from N-terminal of human hnRNP L.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total hnRNP L protein.

Applications:

WB IHC IF

Background:

Splicing factor binding to exonic or intronic sites and acting as either an activator or repressor of exon inclusion. Exhibits a binding preference for CA-rich elements. Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes and associated with most nascent transcripts. Associates, together with APEX1, to the negative calcium responsive element (nCaRE) B2 of the APEX2 promoter.

Pinol-Roma S., J. Cell Biol. 109:2575-2587(1989).
Ito M., Cancer Res. 61:2038-2046(2001).
Rasmussen H.H., Electrophoresis 13:960-969(1992).

References:

appl_detail:

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100
Immunofluorescence: 1:100~1:500

Datasheet PDF