HMGB1 Antibody

Catalog Number:

33661

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P09429
NCBI Gene ID: 3146

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human HMGB1.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total HMGB1 protein.

Applications:

WB

Background:

DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS). Heparin-binding protein that has a role in the extension of neurite-type cytoplasmic processes in developing cells By similarity.

Wen L., Nucleic Acids Res. 17:1197-1214(1989).
Ferrari S., Genomics 35:367-371(1996).
Rasmussen R.K., Electrophoresis 18:588-598(1997).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF