MYST2 Antibody

Catalog Number:

33629

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: O95251
NCBI Gene ID: 11143

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human MYST2.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total MYST2 protein.

Applications:

WB IF

Background:

Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Through chromatin acetylation it may regulate DNA replication and act as a coactivator of TP53-dependent transcription. Specifically represses AR-mediated transcription.

Iizuka M., J. Biol. Chem. 274:23027-23034(1999).
Sharma M., J. Biol. Chem. 275:35200-35208(2000).
Olsen J.V., Cell 127:635-648(2006).

References:

appl_detail:

Western blotting: 1:500~1:3000

Immunofluorescence: 1:100~1:500

Datasheet PDF