ADA2L Antibody

Catalog Number:

33614

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: O75478
NCBI Gene ID: 6871

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human ADA2L.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total ADA2L protein.

Applications:

WB

Background:

Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. Required for the function of some acidic activation domains, which activate transcription from a distant site By similarity. Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling.

Candau R., Mol. Cell. Biol. 16:593-602(1996).
Ogryzko V.V., Cell 94:35-44(1998).
Henriksson A., Mol. Cell. Biol. 17:3065-3073(1997).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF