DNA Polymerase ζ Antibody

Catalog Number:

33602

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: O60673
NCBI Gene ID: 5980

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human DNA Polymerase ζ.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total DNA Polymerase ζ protein.

Applications:

IHC

Background:

Interacts with MAD2L2 to form the error prone DNA polymerase zeta involved in translesion DNA synthesis.

Gibbs P.E.M., Proc. Natl. Acad. Sci. U.S.A. 95:6876-6880(1998).
Lin W., Mutat. Res. 433:89-98(1999).
Morelli C., Cytogenet. Cell Genet. 83:18-20(1998).

References:

appl_detail:

Immunohistochemistry: 1:50~1:100

Datasheet PDF