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EPHB6 Antibody

Catalog Number:

33577
other_names: EPB6; Ephrin type-B receptor 6 precursor; HEP; Tyrosine-protein kinase-defective receptor EPH-6;

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot: O15197
NCBI Gene ID: 2051

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human EPHB6.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total EPHB6 protein.

Applications:

WB IHC IF

Background:

Kinase-defective receptor for members of the ephrin-B family. Binds to ephrin-B1 and ephrin-B2. Modulates cell adhesion and migration by exerting both positive and negative effects upon stimulation with ephrin-B2. Inhibits JNK activation, T-cell receptor-induced IL-2 secretion and CD25 expression upon stimulation with ephrin-B2.

atsuoka H., Biochem. Biophys. Res. Commun. 235:487-492(1997).
Hillier L.W., Nature 424:157-164(2003).
Zhang Z., Protein Sci. 13:2819-2824(2004).

References:

appl_detail:

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100
Immunofluorescence: 1:100~1:500

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