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GAK Antibody

Catalog Number:

33573
other_names: Cyclin G-associated kinase; EC 2.7.11.1; kinase GAK;

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot: O14976
NCBI Gene ID: 2580

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from Internal of human GAK.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total GAK protein.

Applications:

WB IHC

Background:

Associates with cyclin G and CDK5. Seems to act as an auxilin homolog that is involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1.

Kimura S.H., Genomics 44:179-187(1997).
The MGC Project Team; Genome Res. 14:2121-2127(2004).
Greener T., J. Biol. Chem. 275:1365-1370(2000).

References:

appl_detail:

Western blotting: 1:500~1:3000

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