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SENP8 Antibody

Catalog Number:

33524
other_names: DEN1; NEDP; DENEDDYLASE 1; NEDD8-SPECIFIC PROTEASE 1; SENTRIN-SPECIFIC PROTEASE FAMILY

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q96LD8
NCBI Gene ID: 123228

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from Internal of human SENP8.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total SENP8 protein.

Applications:

WB IHC

Background:

Protease that catalyzes two essential functions in the NEDD8 pathway: processing of full-length NEDD8 to its mature form and deconjugation of NEDD8 from targeted proteins such as cullins or p53.

Tudeviin Gan-Erdene, J. Biol. Chem., Aug 2003; 278: 28892 - 28900.
Debaditya Mukhopadhyay, J. Cell Biol., Sep 2006; 174: 939 - 949.
Thomas Colby, Plant Physiology, Sep 2006; 142: 318 - 332.
Joris Hemelaar, Mol. Cell. Biol., Jan 2004; 24: 84 - 95.

References:

appl_detail:

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100

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