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SENP7 Antibody

Catalog Number:

33523
other_names: Sentrin-specific protease 7; EC 3.4.22.-; Sentrin/SUMO-specific protease SENP7; SUMO-1-specific protease 2; SUMO1/sentrin specific protease 7

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q9BQF6
NCBI Gene ID: 57337

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from Internal of human SENP7.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total SENP7 protein.

Applications:

WB IHC

Background:

Protease that deconjugates SUMO2 and SUMO3 from targeted proteins, but not SUMO1. Catalyzes the deconjugation of poly-SUMO2 and poly-SUMO3 chains. Has very low efficiency in processing full-length SUMO proteins to their mature forms.

Debaditya Mukhopadhyay, J. Cell Biol., Sep 2006; 174: 939 - 949.
Alessandra Di Bacco, Mol. Cell. Biol., Jun 2006; 26: 4489 - 4498.
Henrik Andersson, J. Med. Microbiol., Aug 2006; 55: 1023 - 1033.
Il-Jin Kim, Carcinogenesis, Mar 2006; 27: 392 - 404.

References:

appl_detail:

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100

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