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SENP5 Antibody

Catalog Number:

33521
other_names: EC 3.4.22.-; SUMO1/sentrin specific peptidase 5;

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q96HI0
NCBI Gene ID: 205564

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from Internal of human SENP5.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total SENP5 protein.

Applications:

WB IHC

Background:

Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO3 to its mature form and deconjugation of SUMO2 and SUMO3 from targeted proteins. Has weak proteolytic activity against full-length SUMO1 or SUMO1 conjugates. Required for cell division.

Alessandra Di Bacco, Mol. Cell. Biol., Jun 2006; 26: 4489 - 4498.
Thomas Colby, Plant Physiology, Sep 2006; 142: 318 - 332.
Pei-Zheng Zheng, PNAS, May 2005; 102: 7653 - 7658.
Rodolfo Zunino, J. Cell Sci., Apr 2007; 120: 1178 - 1188.

References:

appl_detail:

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100

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