NCoR1 Antibody

Catalog Number:

33512

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: O75376
NCBI Gene ID: 9611

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from Internal of human NCoR1.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total NCoR1 protein.

Applications:

WB IHC

Background:

Mediates transcriptional repression by certain nuclear receptors. Part of a complex which promotes histone deacetylation and the formation of repressive chromatin structures which may impede the access of basal transcription factors. Participates in the transcriptional repressor activity produced by BCL6.

Igor Girault, Clin. Cancer Res., Apr 2003; 9: 1259.
Xinjian Peng, Carcinogenesis, May 2007; 28: 1000 - 1007.
Satoshi Mikawa, Genome Res., May 2007; 17: 586 - 593.
Claire M. Banwell, Clin. Cancer Res., Apr 2006; 12: 2004 - 2013.

References:

appl_detail:

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100

Datasheet PDF