TGF alpha Antibody

Catalog Number:

33499

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P01135
NCBI Gene ID: 7039

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from human TGF alpha.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total TGF alpha protein.

Applications:

WB IHC

Background:

TGF alpha is a mitogenic polypeptide that is able to bind to the EGF receptor/EGFR and to act synergistically with TGF beta to promote anchorage-independent cell proliferation in soft agar.

Barbara D. Abbott, Toxicol. Sci., Jan 2003; 71: 84 - 95.
L Shum, J. Cell Biol., May 1994; 125: 903.
M.J. Donnelly, Carcinogenesis, May 1993; 14: 981 - 985.
T Marchbank, Gut, Dec 2002; 51: 787 - 792.

References:

appl_detail:

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100

Datasheet PDF