Retinoid X Receptor γ Antibody

Catalog Number:

33481

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P48443
NCBI Gene ID: 6258

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from human Retinoid X Receptor γ antibody.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total Retinoid X Receptor γ protein.

Applications:

WB IHC IF

Background:

Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for RXRs is 9-cis retinoic acid By similarity.

Hideki Chiba, J. Cell Biol., Nov 1997; 139: 735.
KS Miyata, J. Biol. Chem., Sep 1993; 268: 19169 - 19172.
Deborah L. Osburn, Mol. Cell. Biol., Aug 2001; 21: 4909 - 4918.
Isabelle M. L. Billas, J. Biol. Chem., Mar 2001; 276: 7465 - 7474.

References:

appl_detail:

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100
Immunofluorescence: 1:100~1:500

Datasheet PDF