PDGFB Antibody

Catalog Number:

33469

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P01127
NCBI Gene ID: 5155

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from human PDGFB.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total PDGFB protein.

Applications:

WB

Background:

Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFA By similarity.

Li Fang, Arterioscler. Thromb. Vasc. Biol., Apr 2004; 24: 787 - 792.
EJ Battegay, J. Cell Biol., May 1994; 125: 917.
RA Seifert, J. Biol. Chem., Feb 1993; 268: 4473 - 4480.
Jason Liu, Am J Physiol Lung Cell Mol Physiol, May 1998; 274: 702.

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF