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p15 INK Antibody

Catalog Number:

33457
other_names: CDKN2B; CDN2B; Cyclin-dependent kinase 4 inhibitor B; MTS2; Multiple tumor suppressor 2

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot: P42772
NCBI Gene ID: 1030

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from human p15 INK antibody.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total p15 INK protein.

Applications:

WB IHC IF

Background:

Interacts strongly with CDK4 and CDK6. Potent inhibitor. Potential effector of TGF-beta induced cell cycle arrest.

Nynke Y. Rots, Blood, Apr 1999; 93: 2721 - 2729.
Stefan Faderl, Clin. Cancer Res., Jul 1999; 5: 1855.
George Wu, Mol. Biol. Cell, Mar 2007; 18: 1018 - 1029.
A. Koenig, Vet. Pathol., Jul 2002; 39: 458.

References:

appl_detail:

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100
Immunofluorescence: 1:100~1:500

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