MMP-3 Antibody

Catalog Number:

33443

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P08254
NCBI Gene ID: 4314

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from human MMP-3.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total MMP-3 protein.

Applications:

WB IHC

Background:

Can degrade fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. Activates procollagenase.

H.R. Lijnen, J Blood, Mar 1998; 91: 2045 - 2053.
TJ Housley, J. Biol. Chem., Feb 1993; 268: 4481 - 4487.
J. Silence, Arterioscler. Thromb. Vasc. Biol., Sep 2001; 21: 1440.
M. J. Green, Rheumatology, Jan 2003; 42: 83 - 88.

References:

appl_detail:

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100

Datasheet PDF