iNOS Antibody

Catalog Number:

33424

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P35228
NCBI Gene ID: 4843

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from human iNOS.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total iNOS protein.

Applications:

WB IHC IF

Background:

Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such COX2.

Rachel J. Jones, Am J Physiol Heart Circ Physiol, Jun 2007; 292: H2634 - H2642.
Katrin Linker,Nucleic Acids Res., Aug 2005; 33: 4813 - 4827.
Donna-Marie McCafferty,Donna-Marie McCafferty,
Lian-Qun Qiu, J. Am. Soc. Nephrol., Aug 2004; 15: 2066 - 2078.

References:

appl_detail:

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100
Immunofluorescence: 1:100~1:500

Datasheet PDF