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HSP60 Antibody

Catalog Number:

33408
other_names: CPN60; CHAPERONIN 60-KD; GroEL E. COLI HOMOLOG OF HEAT-SHOCK 60-KD PROTEIN 1; heat shock 60kDa protein 1 (chaperonin);

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot: P10809
NCBI Gene ID: 3329

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from human HSP60.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total HSP60 protein.

Applications:

WB IHC IF

Background:

Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix. HAMAP-Rule MF_00600

Sung Gyoo Park, J. Biol. Chem., Oct 2003; 278: 39851 - 39857.
Zhiming Mai, Mol. Cell. Biol., Mar 1999; 19: 2198 - 2205.
Hideaki Itoh, Eur. J. Biochem., Dec 2002; 269: 5931.
Jonathan D. Cechetto, J. Histochem. Cytochem., Jan 2000; 48: 45.

References:

appl_detail:

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100
Immunofluorescence: 1:100~1:500

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