GluR8 Antibody

Catalog Number:

33391

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: O00222
NCBI Gene ID: 2918

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from human GluR8.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total GluR8 protein.

Applications:

WB IHC

Background:

G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.

Patrick. M. Downey, J Biomol Screen, Dec 2005; 10: 841 - 848.
RJ Wenthold, J. Biol. Chem., Jan 1994; 269: 1332 - 1339.
Toshiaki Watanabe, Cancer Res., Oct 2006; 66: 9804 - 9808.
V. Bruno, J. Neurosci., Sep 2000; 20: 6413.

References:

appl_detail:

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100

Datasheet PDF