GluR7 Antibody

Catalog Number:

33390

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q14831
NCBI Gene ID: 2917

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from human GluR7.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total GluR7 protein.

Applications:

WB IHC

Background:

G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.

Hans H. Schiffer, J. Neurosci., Dec 2000; 20: 9025.
Nathalie Strutz, J. Neurosci., Jan 2001; 21: 401.
Fr¨¦d¨¦ric Jaskolski, J. Biol. Chem., Jun 2005; 280: 22968 - 22976.
DE Hamassaki-Britto, J. Neurosci., May 1993; 13: 1888.

References:

appl_detail:

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100

Datasheet PDF