Ezrin Antibody

Catalog Number:

33368

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P15311
NCBI Gene ID: 7430

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from human Ezrin.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total Ezrin protein.

Applications:

WB IHC

Background:

Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis.

Lixin Zhu, Am J Physiol Cell Physiol, Jun 2005; 288: C1242 - C1254.
H.J. Spence, Hum. Mol. Genet., Aug 2004; 13: 1657 - 1668.
Vera L¨²cia Bonilha, J. Cell Biol., Dec 1999; 147: 1533.
M Berryman, J. Cell Biol., Dec 1995; 131: 1231.

References:

appl_detail:

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100

Datasheet PDF