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Cyclin G Antibody

Catalog Number:

33353
other_names: Ribosomal protein S6 kinase I; S6K; S6K1; 70 kDa ribosomal protein S6 kinase 1; p70 S6 kinase alpha

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot: P51959
NCBI Gene ID: 900

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from human Cyclin G.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total Cyclin G protein.

Applications:

WB IHC

Background:

May play a role in growth regulation. Is associated with G2/M phase arrest in response to DNA damage. May be an intermediate by which p53 mediates its role as an inhibitor of cellular proliferation By similarity.

Philip J. Papst, et al. (1998) J. Biol. Chem; 273: 15077.
Satoru Eguchi, et al. (999) J. Biol. Chem 1; 274: 36843.
Ana Gonz¨¢lez-Garc¨ªa, et al. (2002) J. Biol. Chem; 277: 1500-1508.
Ulrike Krause, et al. (2002) Eur. J. Biochem; 269: 3751.

References:

appl_detail:

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100

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