Claudin 10 Antibody

Catalog Number:

33338

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P78369
NCBI Gene ID: 9071

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from human Claudin 10.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total Claudin 10 protein.

Applications:

WB

Background:

Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. May form permselective paracellular pores; isoform 1 appears to create pores preferentially permeable to cations and isoform 2 for anions. Plays a key role in controlling cation selectivity and transport in the thick ascending limb (TAL) of Henle's loop in kidney.

Siu Tim Cheung, Clin. Cancer Res., Jan 2005; 11: 551 - 556.
Hiroki Fujita, J. Histochem. Cytochem., Aug 2006; 54: 933 - 944.
Christina M. Van Itallie, Am J Physiol Renal Physiol, Dec 2006; 291: F1288 - F1299.
Anne Florin, Endocrinology, Mar 2005; 146: 153

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF