53BP1 (Ab-29) Antibody

Catalog Number:

33270

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q12888
NCBI Gene ID: 7158

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from Internal of human 53BP1.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total 53BP1 protein.

Applications:

WB

Background:

Plays a key role in the response to DNA damage. May have a role in checkpoint signaling during mitosis. Enhances TP53-mediated transcriptional activation.

Iwabuchi K., J. Biol. Chem. 273:26061-26068(1998).
Nakajima D., Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
Bechtel S., BMC Genomics 8:399-399(2007).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF