Androgen Receptor (Ab-363) Antibody

Catalog Number:

33255

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P10275
NCBI Gene ID: 367

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized non-phosphopeptide derived from human Androgen Receptor around the phosphorylation site of tyrosine 363 (D-Y-Y(p)-N-F).

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total Androgen Receptor protein.

Applications:

WB

Background:

Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins. Transcription activation is down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3.

Lubahn D.B., Mol. Endocrinol. 2:1265-1275(1988).
Lubahn D.B., Proc. Natl. Acad. Sci. U.S.A. 86:9534-9538(1989).
Govindan M.V.; Mol. Endocrinol. 4:417-427(1990).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF