GluR5 Antibody

Catalog Number:

33388

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P39086
NCBI Gene ID: 2897

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from human GluR5.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total GluR5 protein.

Applications:

WB IHC

Background:

Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. May be involved in the transmission of light information from the retina to the hypothalamus.

Ana V. Paternain, J. Neurosci., Jan 2000; 20: 196.
Zhao Ren, J. Biol. Chem., Dec 2003; 278: 52700 - 52709.
MICHAEL A. ROGAWSKI, Ann. N.Y. Acad. Sci., Apr 2003; 985: 150.
Yoshinori Sahara, J. Neurosci., Sep 1997; 17: 6611.

References:

appl_detail:

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100

Datasheet PDF