HSF1 (Ab-142) Antibody

Catalog Number:

33215

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q00613
NCBI Gene ID: 3297

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized non-phosphopeptide derived from human HSF1 around the phosphorylation site of threonine 142 (L-L-T(p)-D-V).

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total HSF1 protein.

Applications:

WB

Background:

DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. In higher eukaryotes, HSF is unable to bind to the HSE unless the cells are heat shocked.

Rabindran S.K., Proc. Natl. Acad. Sci. U.S.A. 88:6906-6910(1991).
Ota T., Nat. Genet. 36:40-45(2004).
Kalnine N., Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF