CDC25A (Ab-178) Antibody

Catalog Number:

33209

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P30304
NCBI Gene ID: 993

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized non-phosphopeptide derived from human CDC25A around the phosphorylation site of serine 178 (Q-N-S(p)-A-P).

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total CDC25A protein.

Applications:

WB

Background:

Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Directly dephosphorylates CDK1 and stimulates its kinase activity. Also dephosphorylates CDK2 in complex with cyclin E, in vitro.

Galaktionov K.I.,Cell 67:1181-1194(1991).
The MGC Project Team;Genome Res. 14:2121-2127(2004).
Wegener S., Eur. J. Cell Biol. 79:810-815(2000).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF