Smad1 (Ab-187) Antibody

Catalog Number:

33163

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q15797
NCBI Gene ID: 4086

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized non-phosphopeptide derived from human Smad1 around the phosphorylation site of serine 187 (P-H-S(p)-P-N).

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total Smad1 protein

Applications:

WB IHC IF

Background:

Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1.

Riggins G.J., Nat. Genet. 13:347-349(1996).
Liu F., Nature 381:620-623(1996).
Hoodless P.A., Cell 85:489-500(1996)

References:

appl_detail:

Western blotting: 1:500~1:3000

Immunofluorescence: 1:100~1:500

Datasheet PDF