MCPH1 Antibody

Catalog Number:

32871

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q8NEM0
NCBI Gene ID:79648

Form of Antibody:

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Recombinant protein of human MCPH1.

Purification:

Antibodies were purified by affinity purification using immunogen.

Specificity/Sensitivity:

The antibody detects endogenous level of total MCPH1 protein.

Applications:

WB

Background:

This gene encodes a DNA damage response protein. The encoded protein may play a role in G2/M checkpoint arrest via maintenance of inhibitory phosphorylation of cyclin-dependent kinase 1. Mutations in this gene have been associated with primary autosomal recessive microcephaly 1 and premature chromosome condensation syndrome. Alternatively spliced transcript variants have been described.

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF