ODC1 Antibody

Catalog Number:

32515

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:P11926
NCBI Gene ID:4953

Form of Antibody:

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Recombinant protein of human ODC1.

Purification:

Antibodies were purified by affinity purification using immunogen.

Specificity/Sensitivity:

The antibody detects endogenous level of total ODC1 protein.

Applications:

WB,IHC

Background:

Ornithine decarboxylase (ODC) is also named as ODC1and belongs to the Orn/Lys/Arg decarboxylase class-II family. It catalyzes the conversion of ornithine to putrescine, the first step and a major site of regulation of polyamine biosynthesis. The level of ODC is known to be controlled at several sites, namely transcription, translation, and enzyme degradation. Polyamines can stimulate the degradation of ODC as a type of negative feedback control(PMID:8486633). This protein can be phosphorylated in vivo(PMID:8798774). This antibody is specific to ODC1.

References:

appl_detail:

WB 1:500 - 1:2000
IHC 1:50 - 1:200

Datasheet PDF