U2AF2 Antibody

Catalog Number:

32508

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:P26368
NCBI Gene ID:11338

Form of Antibody:

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Recombinant protein of human U2AF2.

Purification:

Antibodies were purified by affinity purification using immunogen.

Specificity/Sensitivity:

The antibody detects endogenous level of total U2AF2 protein.

Applications:

WB,IF

Background:

U2 auxiliary factor (U2AF), comprised of a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the U2AF large subunit which contains a sequence-specific RNA-binding region with 3 RNA recognition motifs and an Arg/Ser-rich domain necessary for splicing. The large subunit binds to the polypyrimidine tract of introns early during spliceosome assembly. Multiple transcript variants have been detected for this gene, but the full-length natures of only two have been determined to date.

References:

appl_detail:

WB 1:500 - 1:2000
IF 1:50 - 1:100
IP 1:50 - 1:200

Datasheet PDF