c-Jun(Ab-63) Antibody

Catalog Number:

33187

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P05412
NCBI Gene ID: 3725

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized non-phosphopeptide derived from human c-Jun around the phosphorylation site of Serine 63.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of c-Jun protein around Serine 63.

Applications:

WB

Background:

Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation.

Wei W, et al. (2005). Cancer Cell. 8(1): 25-33.
Sevilla A, et al. (2004). Oncogene.23(55): 8950-8958.
Li L, et al. (2004). J Biol Chem.279(6): 4058-4065.
Hurd C, et al. (2002). Oncogene.21(14): 2154-2160.

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF