CUL3 Antibody

Catalog Number:

32149

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q13618
NCBI Gene ID:8452

Form of Antibody:

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Recombinant protein of human CUL3.

Purification:

Antibodies were purified by affinity purification using immunogen.

Specificity/Sensitivity:

The antibody detects endogenous level of total CUL3 protein.

Applications:

WB,IHC,IF

Background:

CUL3 (Cullin-3) is a member of the cullin-based ubiquitin ligase family. By interacting with Hrt1 and BTB domain containing proteins, the complex functions as a CUL3-based E3 ligase to bring specific substrates to ubiquitinylation and degradation (1). The CUL3 complex has been shown to target many substrates involved in cell cycle progression (2), transcription (3), development and differentiation (4,5).

References:

appl_detail:

WB 1:500 - 1:2000
IHC 1:50 - 1:100
IF 1:50 - 1:200

Datasheet PDF