JUP Antibody

Catalog Number:

32095

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:P14923
NCBI Gene ID:3728

Form of Antibody:

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Recombinant protein of human JUP.

Purification:

Antibodies were purified by affinity purification using immunogen.

Specificity/Sensitivity:

The antibody detects endogenous level of total JUP protein.

Applications:

WB,IF

Background:

This gene encodes a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat. Mutation in this gene has been associated with Naxos disease. Alternative splicing occurs in this gene; however, not all transcripts have been fully described.

References:

appl_detail:

WB 1:500 - 1:2000
IF 1:50 - 1:200
IP 1:50 - 1:100

Datasheet PDF