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HK1/HK2 antibody

Catalog Number:

31975
other_names: HK; HKD; HKI; HXK1; RP79; HMSNR; HK1-ta; HK1-tb; HK1-tc; hexokinase; HKII; HXK2

Amount:

100μg
calculated_mw: 102 kDa
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q8N4E4
NCBI Protein#: BC021116

Form of Antibody:

pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Storage/Stability:

Immunogen:

Fusion protein of human HK1/HK2

Purification:

Antigen affinity purification

Specificity/Sensitivity:

Applications:

WB, IHC

Background:

Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in several transcript variants which encode different isoforms, some of which are tissue-specific.

References:

appl_detail:

WB dilution:1:1000-1:5000
IHC dilution:1:100-1:300

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