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Catalog Number: |
31973 |
| other_names: | VIIAL; COX7AL; COX7AL1; COXVIIAL; COXVIIa-L |
Amount: |
100μg |
| calculated_mw: | 9 kDa |
| host_species: | Rabbit |
Price: |
$319 |
Swiss-Prot No: |
Swiss-Prot#: Q8IVL5 |
Form of Antibody: |
pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Storage/Stability: |
|
Immunogen: |
Synthetic peptide of human COX7A2 |
Purification: |
Antigen affinity purification |
Specificity/Sensitivity: |
|
Applications: |
WB, IHC |
Background: |
Cytochrome c oxidase, the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of three catalytic subunits encoded by mitochondrial genes, and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, while the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 2 (liver isoform) of subunit VIIa, with this polypeptide being present in both muscle and non-muscle tissues. In addition to polypeptide 2, subunit VIIa includes polypeptide 1 (muscle isoform), which is present only in muscle tissues, and a related protein, which is present in all tissues. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 4 and 14. |
References: |
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appl_detail: |
WB dilution:1:200-1:1000 |
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